7 Night U.S. East Coast Cruise
Cruise LineAmerican Cruise Lines
ShipIndependence
DepartsSat, Apr 4th 2026
ReturnsSat, Apr 11th 2026
Nights7
Departing PortJacksonville
Ports of CallJacksonville, Amelia Island, Jekyll Island, St. Simons Island, Savannah, Hilton Head Island, Beaufort, Charleston
The Independence is equipped with the largest staterooms in the industry with most suites featuring private balconies. With the latest in navigation and safety technology, the Independence is fully stabilized, allowing American Cruise … 
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7 Night U.S. East Coast Cruise
Cruise LineAmerican Cruise Lines
ShipIndependence
DepartsSat, Apr 11th 2026
ReturnsSat, Apr 18th 2026
Nights7
Departing PortCharleston
Ports of CallCharleston, Beaufort, Hilton Head Island, Savannah, St. Simons Island, Jekyll Island, Amelia Island, Jacksonville
The Independence is equipped with the largest staterooms in the industry with most suites featuring private balconies. With the latest in navigation and safety technology, the Independence is fully stabilized, allowing American Cruise …
Inside Cabin
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Ocean View
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Balcony
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Suite
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6 Night Canada - New England Cruise
Cruise LineAmerican Cruise Lines
ShipIndependence
DepartsSat, Apr 11th 2026
ReturnsFri, Apr 17th 2026
Nights6
Departing PortBaltimore
Ports of CallBaltimore, Yorktown, Crisfield, Cambridge, St. Michaels, Annapolis, Baltimore
The Independence is equipped with the largest staterooms in the industry with most suites featuring private balconies. With the latest in navigation and safety technology, the Independence is fully stabilized, allowing American Cruise …
Inside Cabin
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Ocean View
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Balcony
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Suite
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14 Night U.S. East Coast Cruise
Cruise LineAmerican Cruise Lines
ShipIndependence
DepartsSat, Apr 18th 2026
ReturnsSat, May 2nd 2026
Nights14
Departing PortJacksonville
Ports of CallJacksonville, Fernandina Beach, Jekyll Island, St. Simons Island, Savannah, Hilton Head Island, Beaufort, Charleston, East Coast Inland Passage, Wilmington, Beaufort, Kitty Hawk, Norfolk, St. Michaels, Baltimore
The Independence is equipped with the largest staterooms in the industry with most suites featuring private balconies. With the latest in navigation and safety technology, the Independence is fully stabilized, allowing American Cruise …
Inside Cabin
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Ocean View
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Balcony
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Suite
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6 Night Canada - New England Cruise
Cruise LineAmerican Cruise Lines
ShipIndependence
DepartsSat, Apr 18th 2026
ReturnsFri, Apr 24th 2026
Nights6
Departing PortBaltimore
Ports of CallBaltimore, Yorktown, Crisfield, Cambridge, St. Michaels, Annapolis, Baltimore
The Independence is equipped with the largest staterooms in the industry with most suites featuring private balconies. With the latest in navigation and safety technology, the Independence is fully stabilized, allowing American Cruise …
Inside Cabin
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Ocean View
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Balcony
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Suite
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6 Night Canada - New England Cruise
Cruise LineAmerican Cruise Lines
ShipIndependence
DepartsSat, Apr 25th 2026
ReturnsFri, May 1st 2026
Nights6
Departing PortBaltimore
Ports of CallBaltimore, Yorktown, Crisfield, Cambridge, St. Michaels, Annapolis, Baltimore
The Independence is equipped with the largest staterooms in the industry with most suites featuring private balconies. With the latest in navigation and safety technology, the Independence is fully stabilized, allowing American Cruise …
Inside Cabin
Call for pricing
Ocean View
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Balcony
Call for pricing
Suite
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Prices are per person, double occupancy, cruise only and on select sailings. Prices shown are for stateroom categories as noted and are shown in US Dollars. Pricing listed includes taxes and fees. Airfare is not included. Prices and itineraries are based on availability and are subject to change without notice.
